SPONSORED CONTENT -- (StatePoint) Cindy has always been active. As a physical education teacher, and later an elementary school principal, she built her career around helping others lead healthy, fulfilling lives. But behind that active lifestyle, she was on a decades-long search for answers about her respiratory health.
Bronchiectasis is a chronic inflammatory lung disease that can worsen over time. People living with the disease often experience symptoms such as a chronic cough, excess mucus, and recurrent lung infections that may overlap with other respiratory diseases like chronic obstructive pulmonary disease (COPD) or asthma. An estimated 500,000 adults in the United States are diagnosed with bronchiectasis, and it’s believed that even more may be living with the disease. Though bronchiectasis is chronic and irreversible, there are treatments and disease management plans for people living with the disease.
Prior to her diagnosis, Cindy experienced years of chronic cough accompanied by mucus and shortness of breath, but doctors couldn’t settle on a definitive diagnosis. Despite seeing multiple specialists for repeated diagnostic testing and receiving treatment for several respiratory conditions, including potential COPD, her symptoms continued. In 2021, after being referred to a new pulmonologist, COPD was ruled out and a CT scan confirmed bronchiectasis. Cindy was given a nebulizer to use once a day, and up to twice a day as needed.
“Nothing much changed,” Cindy recalls. “I was often too sick or too exhausted to carry on with activities. I kept my family in the dark about the severity of my illness and just tried to push through.”
After a particularly severe coughing episode a few years after her diagnosis, Cindy decided to take a more active role in her care, seeking information and partnering with another pulmonologist to explore additional treatment options.
It was time for a different approach.
In November 2025, Cindy started once-daily BRINSUPRI® (brensocatib), the first and only FDA-approved treatment indicated for non-cystic fibrosis bronchiectasis in people 12 years and older. The most common side effects with treatment include upper respiratory tract infection, headache, rash, dry skin, small areas of skin thickening, and high blood pressure. For more information, visit https://www.brinsupri.com/.
“With BRINSUPRI and a correct diagnosis, I can laser focus on managing my bronchiectasis. Although my health journey of almost 40 years has been long, I’m now more than 10 months into treatment, and BRINSUPRI has made a difference for me,” says Cindy. Individual results may vary.
This article is sponsored by Insmed.
What is BRINSUPRI?
BRINSUPRI is a prescription medicine used to treat non-cystic fibrosis bronchiectasis (NCFB) in adults and children 12 years of age and older. It is not known if BRINSUPRI is safe and effective in children under 12 years of age.
IMPORTANT SAFETY INFORMATION
Before taking BRINSUPRI, tell your healthcare provider about all of your medical conditions, including if you:
• have recently received or are scheduled to receive any live attenuated vaccinations.
• are pregnant or plan to become pregnant. It is not known if BRINSUPRI will harm your unborn baby.
• are breastfeeding or plan to breastfeed. It is not known if BRINSUPRI passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during this time.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Do not change or stop your medicines unless your healthcare provider tells you to.
BRINSUPRI may cause serious side effects including:
• Skin problems. Tell your healthcare provider about any new skin symptoms. Your healthcare provider may send you to a dermatologist for an examination, if needed.
• Dental problems. Get regular dental checkups while taking BRINSUPRI. Brush and clean your teeth as recommended by your dentist. Tell your healthcare provider and contact your dentist if you experience new gum (gingival) or teeth (dental) symptoms.
Common side effects of BRINSUPRI:
The most common side effects of BRINSUPRI include upper respiratory tract infection, headache, rash, dry skin, small areas of skin thickening (hyperkeratosis), and high blood pressure (hypertension).
Less common side effects include abnormal liver blood test, hair loss (alopecia), and skin cancers.
These are not all of the possible side effects of BRINSUPRI.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
Please see full Prescribing Information and Patient Information at BRINSUPRI.com.
PP-BRIN-US-00838 10/2026
